University of Lethbridge

Biography

Teaching

Introductory genetics
Developmental biology
Molecular genetics
Plant Developmental Genetics

Selected Publications

Dhakal,S., Reiter,J.W*. Laroche, A. and Schultz, E.A. 2021. Leaf vein pattern response to heat and drought requires UNHINGED, FORKED1 and FORKED-LIKE genes and is mimicked by ABA treatment. Environmental and Experimental Botany 185.

Prabhakaran Mariyamma, N., Clarke, K.J., Yu, H., Wilton, E.*, Van Dyk, J.*, Hou, H. and Schultz, E.A. 2018. Members of the Arabidopsis FORKED1-LIKE gene family act to localize PIN1 in developing veins. Journal of Experimental Botany 69: 4773-4790.

Prabhakaran Mariyamma, N., Hou, H., Carland, F.M., Nelson, T. and Schultz, E.A. 2017. Localization of Arabidopsis FORKED1 to a RABA-positive compartment suggests a role in secretion. Journal of Experimental Botany 68: 3375-3390.

Li, G., Hu, S., Yang, J., Schultz, E.A., Clarke, K.J., and Hou, H. 2017. Water-Wisteria as an ideal plant to study heterophylly in higher plants. Plant Cell Reports 36: 1225-1236.

Pahari, S., Cormack, R.D., Blackshaw, M.T.*, Liu, C., Erickson, J.L., Schultz, E.A. 2014. UNHINGED encodes a VPS51 homologue of Arabidopsis and reveals a role for the GARP complex in leaf vein patterning. Development 141: 1894-1905.

Garrett, J.J., Meents, M.J.*, Blackshaw, M.T.*, Blackshaw, L.C.*, Hou, H., Styranko, D.M., Kohalmi, S.E., Schultz, E.A. 2012. A novel, semi-dominant allele of MONOPTEROS provides insight into leaf initiation and vein pattern formation. Planta. 236: 297-37.

Hou, H, Erickson, J., Meservy, J. and E. Schultz. 2010. FORKED1 encodes a PH domain protein that is required for PIN1 localization in developing leaf veins. The Plant Journal 63:6: 960-973.

Zgurski, J.M., Sharma, R., Bolokoski, D.A., and Schultz, E.A. 2005. Asymmetric auxin distribution precedes asymmetric growth and differentiation in asymmetric leaf1 and asymmetric leaf2 Arabidopsis leaves. Plant Cell 17:77-91.

Steynen, Q.J., and Schultz, E.A. 2003. The FORKED genes are essential for distal vein-meeting in Arabidopsis. Development 130, 4695-4708.

Steynen, Q.J., Bolokoski, D.A. and Schultz, E.A. 2001. Alteration in flowering time causes accelerated or decelerated progression through Arabidopsis vegetative phases. Canadian Journal of Botany 79: 657-665.

Schultz, E.A., Carpenter, R., Doyle, S. and E. S. Coen. 2001. Fimbriata interacts non-cell autonomously with floral regulatory genes. The Plant Journal 25: 499-508.

Ingram, G.C., Doyle, S., Carpenter, R., Schultz, E.A., Simon, R. and E. S. Coen. 1997. Dual role for fimbriata in regulating floral homeotic genes and cell division in Antirrhinum . EMBO J. 16: 6521-6534.

Haughn, G.W., Schultz, E.A., Martinez-Zapater, J. 1995. The regulation of flowering in Arabidopsis thaliana: meristems, morphogenesis and mutants. Canadian Journal of Botany 73: 959-981.

Schultz, E.A. and Haughn, G.W. 1993. Regulation of the floral initiation process (FLIP) in Arabidopsis. Development 119: 745-765.

Schultz, E.A., Pickett, F.B., Haughn, G.W. 1991. The FLO10 gene product regulates the expression domain of homeotic genes AP3 and PI in Arabidopsis flowers. The Plant Cell 3: 1221-1237.

Research Interests

Research

We study the mechanism that causes vein differentiation and formation of vein pattern within the model plant Arabidopsis. Arabidopsis leaves produce a complex interconnecting or closed vein pattern Veins are critical to plant structure and function, since they provide both transportation routes and structural support.

As well, vein cells are a classic example of the establishment of cellular asymmetry. Developing vein cells are characterized by the ability to transport the hormone auxin in a directional fashion. Auxin causes induction of vascular fate. Thus, the transport of auxin from one vein cell to the next results in a continuous file of cells that will become the vein. The transport of auxin is directed by the PINFORMED1 protein. In veins, this protein is localized to only one cell face resulting in directional transport.

We are studying a novel set of genes that when mutated, result in an open vein pattern. These genes seem to be required for proper localization of the PINFORMED1 protein. Our experiments are directed towards understanding how the the gene products fit into the mechanisms that establishes asymmetric PIN1 localization.

Internet Links

The University of Lethbridge
The University of Lethbridge
Schultz Lab website