Campus Directory: Ute Wieden-Kothe

University of Lethbridge

Ute Wieden-Kothe
Chemistry & Biochemistry
Office: SA9118
Phone: (403) 332-5274
Room: SA9148


M.Sc. (Biochemistry), Ph.D. (Physical Biochemistry)


RNA, Protein, Ribonucleoprotein, Rapid kinetics, Fluorescence spectroscopy, Crosslinking, Primer extension analysis, Immuno blotting, Chromatography, Ultracentrifugation, Electrophoresis, Molecular cloning, Mutagenesis;yeast genetics

Research Areas

H/ACA small ribonucleoproteins, Ribosome biogenesis, RNA modification, Pseudouridine, RNA-protein interactions, Dyskeratosis congenita

Previous Research Areas

Protein synthesis, Ribosome, mRNA, tRNA, GTPase, Translation, Decoding, Elongation Factors, Accuracy

Alternate Languages


Current Research and Creative Activity

TitleLocationGrant InformationPrincipal InvestigatorCo Researchers
Functional Biochemistry of H/ACA small ribonucleoproteins Lethbridge University of Lethbridge Start-up funding, $115.000, 2006-2009.

U. Kothe, University of Lethbridge
Molecular Mechanisms of Small Ribonucleoproteins Lethbridge CFI, ASRA, University of Lethbridge, $329,440, 2008.

U. Kothe, University of Lethbridge

Previous Research

TitleGrant AgencyCompletion Date
Dissecting the molecular mechanism of aminoacyl-tRNA selection by the ribosome German National Academic Foundation & University of Witten/Herdecke 2006
Functional role of helix D of Elongation Factor Tu during interaction with the Ribosome German National Academic Foundation (Studienstiftung des deutschen Volkes) 2002

Internet Links

Kothe Research lab

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